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Adrian Au Laboratory

Ophthalmic Imaging, AI, and Retinal Genomics

Integrating AI, imaging, and genomics for curing retinal disease

Dr. Adrian Au

Adrian Au, M.D., Ph.D.

Assistant Professor

  • Department of Ophthalmology
  • Jules Stein Eye Institute

Dr. Adrian Au applies machine learning algorithms to ocular imaging modalities, including fundus photography and optical coherence tomography (OCT), to extract and quantify retinal biomarkers associated with disease phenotypes. His research emphasizes the integration of these imaging-derived features with genomic datasets to elucidate the molecular and genetic underpinnings of retinal pathology.

Through the fusion of deep learning-based image analysis and genomic frameworks, Dr. Au seeks to advance our understanding of the biological mechanisms driving disease onset, progression, and therapeutic response. His work operates at the intersection of ophthalmology, computational biology, and precision medicine, with the aim of developing clinically translatable tools for personalized diagnostics and targeted interventions in retinal disease.

Research Focus Areas:

  • Machine learning and deep learning for ocular imaging analysis
  • Integration of imaging biomarkers with genomic data
  • Computational approaches to understanding retinal disease mechanisms
  • Development of AI-driven diagnostic and prognostic tools
  • Precision medicine approaches for personalized retinal disease treatment

Lab Members

Recent Publications

VITRECTOMY FOR PROLIFERATIVE DIABETIC RETINOPATHY WITH ASTEROID HYALOSIS

Justin S. Yun, Erin NaPier, Hamid Hosseini, Adrian C. Au

Retina (2026)

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VKH-Like Syndrome in a Patient on Tofacitinib

Jessica H. Tran, Hamid Hosseini, Edmund Tsui, Adrian Au

Journal of VitreoRetinal Diseases (2026)

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Difluprednate and Loratadine in the Treatment of Pachychoroid Disease Spectrum

Emile R. Vieta-Ferrer, Adrian Au, Jeeyun Ahn, Michael B. Gorin

Journal of Clinical & Translational Ophthalmology (2025)

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Retinal Ischemic Perivascular Lesions Are Associated With Stroke in Individuals With Atrial Fibrillation

Christine Y. Bakhoum, Adrian Au, Elodie Bousquet, Mitchelle Matesva, Maxwell B. Singer, Christina Jayaraj, et al.

Journal of the American Heart Association (2024)

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Retinal Ischemic Perivascular Lesions Are Associated With Myocardial Infarction in Patients With Coronary Artery Disease

Elodie Bousquet, Ahmad Santina, Adrian Au, Swathi Somisetty, Neda Abraham, Shilo Voichanski, et al.

American Journal of Ophthalmology (2024)

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OCT Grading System of Macular Infarction Predicts Vision in Participants With Central Retinal or Hemiretinal Vein Occlusion: A Secondary Analysis of SCORE2

Adrian Au, Michael Ip, Barbara A. Blodi, Ingrid U. Scott, Neal L. Oden, Paul C. Van Veldhuisen, David Sarraf

American Journal of Ophthalmology (2023)

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Progression of Pentosan Polysulfate Sodium Maculopathy in a Prospective Cohort

Swathi Somisetty, Ahmad Santina, Adrian Au, Veronica Romero-Morales, Elodie Bousquet, David Sarraf

American Journal of Ophthalmology (2023)

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Pentosan Polysulfate Sodium-Associated Maculopathy: Early Detection Using OCT Angiography and Choriocapillaris Flow Deficit Analysis

Meira Fogel Levin, Ahmad Santina, Giulia Corradetti, Adrian Au, Anthony Lu, Neda Abraham, et al.

American Journal of Ophthalmology (2022)

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Henle Fiber Layer Hemorrhage in Macular Telangiectasia Type 2: Is Right Eye Dominance Coincidence or Consequence?

Adrian Au, JooYeon Jung, Mark W. Johnson, Caroline Baumal, Mark J. Daily, Julius E.S. Gomolin, et al.

American Journal of Ophthalmology (2022)

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Advanced OCT Analysis of Biopsy-proven Vitreoretinal Lymphoma

FRANCESCO PICHI, ROSA DOLZ-MARCO, JASMINE H. FRANCIS, ADRIAN AU, JANET L. DAVIS, AMANI FAWZI, et al.

American Journal of Ophthalmology (2022)

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