Skip to main content

Ben Glasgow Laboratory

Ophthalmic Pathology and Tear Film Biochemistry

Investigating the molecular mechanisms underlying tear film stability and ocular surface health

Dr. Ben Glasgow

Ben J. Glasgow, M.D.

Professor

  • The Wasserman Professor of Ophthalmology
  • Departments of Pathology and Laboratory Medicine and Ophthalmology
  • Jules Stein Eye Institute

The Glasgow laboratory focuses on understanding the molecular mechanisms that regulate tear film stability and their implications for ocular surface disorders. His research explores the structure and function of tear lipocalins and their interactions with lipids to maintain ocular health.

Key research questions include:

  • What are the structural mechanisms by which tear lipocalins stabilize the tear film?
  • How do lipid-protein interactions contribute to ocular surface health?
  • What roles do tear film components play in protecting against environmental stressors?
  • How can insights into tear film biochemistry inform treatments for dry eye syndrome?
  • What are the molecular pathways involved in lipid layer dysfunction in ocular diseases?

Dr. Glasgow's work integrates biochemistry, structural biology, and clinical studies to advance our understanding of the tear film's role in maintaining a healthy ocular surface. His findings have significant implications for developing therapies for dry eye syndrome and other related conditions.

Selected Publications

Chronic Eosinophilic Leukemia Presenting as Treatment-Refractory Nodular Scleritis: A Paraneoplastic Autoimmune Syndrome With Multisystem Inflammatory Manifestations.

Ji BC, Aung T, Castellino J, Kahlon KS, Tsui E, Glasgow BJ

Cureus (2026)

View Publication

Recognition of Bulbilli Facilitates the Diagnosis of Cladorrhinum bulbillosum.

Chen AC, Ghaffari R, Glasgow BJ

Cornea (2026)

View Publication

Thermotropic phase transitions of binary mixtures of wax and cholesteryl esters relevant to tears.

Glasgow BJ, Abduragimov AR

Biochemistry and Biophysics Reports (2025)

View Publication

Tear Lipocalin and Lipocalin-Interacting Membrane Receptor.

Glasgow BJ

Frontiers in Physiology (2021)

View Publication