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Edmund Tsui Laboratory

Uveitis and Ocular Inflammatory Diseases

Advancing the diagnosis and treatment of uveitis through cutting-edge imaging technologies and clinical trials

Dr. Edmund Tsui

Edmund Tsui, M.D., M.S.

Associate Professor

  • Department of Ophthalmology
  • Jules Stein Eye Institute

The Tsui Research Group is committed to advancing the field of uveitis through innovative imaging analysis, improved diagnostic tools, and clinical trials. By leveraging advanced imaging modalities such as optical coherence tomography, we aim to quantify objectively intraocular inflammation and enhance diagnostic accuracy in uveitis. Our work also includes developing standardized methodologies for assessing inflammation, and conducting clinical trials to evaluate novel therapeutics in the treatment of uveitis and ocular inflammatory disease.

Our research focuses on these areas:

  • Image Analysis: Develop and validate imaging biomarkers using optical coherence tomography (OCT) and other advanced imaging modalities to quantify intraocular inflammation and monitor disease activity in uveitis. This work aims to improve the objectivity of diagnostic assessments, enhance disease monitoring, and guide treatment decisions by leveraging cutting-edge imaging technologies.
  • Advanced Diagnostics: Utilize ocular fluid sampling techniques, such as aqueous and vitreous humor analysis, to improve the diagnosis of uveitis. This includes cytokine profiling, pathogen detection, and biomarker discovery to enable precision diagnostics and uncover underlying etiologies of ocular inflammation.
  • Clinical Trials: Design and conduct clinical trials to evaluate novel therapies and refine treatment strategies for uveitis and other ocular inflammatory diseases. Our research encompasses immune-modulating therapies, biologics, small molecules, and targeted immunotherapies aimed at reducing inflammation, preventing vision loss, and improving patient outcomes.

These research areas reflect our group’s mission to advance the understanding, diagnosis, and treatment of uveitis and ocular inflammatory diseases through innovation and collaboration.

Lab Members

Postdoctoral Scholars

Recent Publications

Pediatric Uveitic Macular Edema in Noninfectious Uveitis <i>Structural and Visual Outcomes and Predictors of Visual Prognosis</i>

Alessandro Feo, Shani Pillar, Paolo Forte, Alberto Quarta, Justin S. Yun, Anamika Patel, …, Edmund Tsui, et al.

OPHTHALMOLOGY RETINA (2026)

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Quantitative Analysis of Retinal Fluid by a Deep Learning Model in Uveitic Macular Edema

Anthony Wu, Adrian Au, Justin Hanson, Marcus Yamamoto, Joy Cheng, Simon Lee, …, Edmund Tsui, et al.

OPHTHALMOLOGY SCIENCE (2026)

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Imaging Measures for the Assessment of Disease Activity in Noninfectious Posterior Uveitis-Multimodal Imaging in Uveitis (MUV) Taskforce: Report 10

ANIRUDDHA AGARWAL, PRITHVI RAMTOHUL, ALESSANDRO INVERNIZZI, SAPNA GANGAPUTRA, EDMUND TSUI, ANNABELLE A. OKADA, …, Edmund Tsui, et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2026)

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Mirvetuximab Soravtansine Exposure and Incidence of Cataract Surgery

Jordyn F. Silverstein, Alexandra Smick, Edmund Tsui, Oladunni Alomaja, Bridget Johnson, Chi-Hong Tseng, et al.

JAMA NETWORK OPEN (2026)

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Anterior segment optical coherence tomography in uveitis: A comprehensive review of clinical applications, diagnostic insights, and future directions

Alessandro Feo, Prashant D. Tailor, Adrian Au, Anthony Wu, Ali Haidar, Mario R. Romano, SriniVas R. Sadda, Edmund Tsui

SURVEY OF OPHTHALMOLOGY (2026)

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Expanded Spectrum of Chrysanthemum and Miliary Multifocal Choroiditis With Panuveitis: Novel Imaging and Pathophysiological Insights

Alessandro Feo, Alberto Quarta, Prithvi Ramtohul, Demi Miller, Kareem Moussa, Eric Crowell, K. Bailey Freund, Edmund Tsui

AMERICAN JOURNAL OF OPHTHALMOLOGY (2026)

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Intraretinal hyperreflective foci: Pathophysiology, imaging features, and clinical implications across retinal diseases

Giacomo Boscia, Alessandro Feo, Alberto Quarta, Elisa Stradiotto, Paolo Forte, Alba Chiara Termite, …, Edmund Tsui, et al.

PROGRESS IN RETINAL AND EYE RESEARCH (2026)

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The association between retinal vasculitis and cerebral infarction in systemic autoimmune disorders

Marina Gad El Sayed, Eman Samir Edrees, Edmund Tsui, Yousef Fouad

CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE (2026)

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Ocular Toxic Effects During Mirvetuximab Soravtansine Therapy

Ali J. Haidar, Angela Chen, Judy L. Chen, Saba Al-Hashimi, Reza S. Ghaffari, Simon Fung, …, Edmund Tsui, et al.

JAMA ONCOLOGY (2026)

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VKH-Like Syndrome in a Patient on Tofacitinib

Jessica H. Tran, Hamid Hosseini, Edmund Tsui, Adrian Au

JOURNAL OF VITREORETINAL DISEASES (2026)

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